性格内向而少言寡语的斯蒂芬（盖尔·加西亚·伯纳尔）平日里就是个经常因性格而遭受挫折的人。这一次，他遇到了更大的麻烦。他大脑里时常出现的各种梦境最终让他惹了大祸。丢掉了工作之后的他决定从墨西哥回到自己的故乡法国巴黎。然而，欧洲忙碌的生活使得他那充满想像力的大脑在庸庸碌碌的日子里显得毫无用处。偶然间，他有幸结识了漂亮大方的女邻居斯蒂芬妮（夏洛特·甘斯博格），经过短暂的交往之后，斯蒂芬发现这个年轻的女人同样具有超强的想像力。两人在一起的时光里深感相见恨晚，于是交往甚笃。但从此之后，斯蒂芬被纷繁的梦境所困扰的日子亦更加的频繁和严重，常遭到梦中人和事的骚扰和纠缠。渐渐地，他在梦境和现实间迷失了方向。享受充足而科学的睡眠似乎也已经是他的一个渴望而不可及的奢望了。但是，经过了众人的帮助之后，“科学睡眠”能解除他的痛苦吗？
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